637 Exploring the impact of immunotherapy on cancer patients' real world experience

Background Background: Immunotherapy (IO) have demonstrated the superior clinical benefits compared to previous anticancer treatments. A better understanding of IO patient experience in real world will allow healthcare professionals develop effective supportive resources, help improve practice and assist patients managing journey. However, little information informational needs are available. This study aims describe cancer experiences from multiple perspectives. Methods cross-sectional qualitative consisted patients, who reported receiving targeting PD1/L-1 receptors irrespective types. The included three independent focus groups, participants were assigned a group based on how long they received treatment prior enrolling study: Focus Group 1 (0–6 months), 2 (6–12 3 (12+ with 4–8 each. Thematic analyses followed deductive approach. Codes themes generated European Organization for Research Treatment Cancer Quality Life Questionnaire (EORTC QLQ-C30). was approved by Ethical & Independent Review Services. Results: 18 total participants, across diagnosed 2006–2020. Fifteen out Caucasian; average age 57.3 years. Participants all groups fatigue as most common side effect, less ability do daily tasks due fatigue, that other same diagnosis provided greatest emotional support, concerns regarding finances/careers, had adjusted their “new normal” satisfied coordination between members team communication oncologist. more concerned recurrence trying figure new roles at home work. Groups mostly unable work diagnosis/treatment this difficult adjustment affected identity. particularly about non-medical expenses insufficient IO. Conclusion: By different time points treatment, providers can accurately address unmet patients' perspective, increase professionals' awareness challenges, support good practices. aid working towards goal improving well-being, ultimately contributing adherence population. Reference Giesinger JM, Kuijpers W, Young T, Tomaszewski KA, Friend E, Zabernigg A, Holzner B, Aaronson NK. Thresholds importance four key domains EORTC QLQ-C30: physical functioning, pain. Health Qual Outcomes 2016; 14 :1–8. Ethics Approval: IRB approval